Thermo Fisher Scientific Gibco KnockOut Serum Replacement
Knockout™ Serum Replacement (Knockout™ SR) is for serum-free, feeder-based culture of embryonic stem cells (ESCs) and induced Pluripotent stem cells (iPSCs) from multiple species. This defined, serum-free formulation directly replaces FBS in existing protocols.
Many of the drawbacks of using FBS in stem cell culture, (differentiation of cells and heat-inactivation) can be alleviated with the use of KnockOut™ Serum Replacement. ES and iPS cells grown in KnockOut™ SR-supplemented media are substantially less differentiated than those grown in FBS-supplemented media, and germline transmission should not be compromised. With over 2000 peer-reviewed publications covering applications such as stem cell culture, differentiation, iPSC generation, ESC derivation, and transgenic modeling, KnockOut™ Serum Replacement is widely cited for stem cell culture.
Many of the drawbacks of using FBS in stem cell culture, (differentiation of cells and heat-inactivation) can be alleviated with the use of KnockOut™ Serum Replacement. ES and iPS cells grown in KnockOut™ SR-supplemented media are substantially less differentiated than those grown in FBS-supplemented media, and germline transmission should not be compromised. With over 2000 peer-reviewed publications covering applications such as stem cell culture, differentiation, iPSC generation, ESC derivation, and transgenic modeling, KnockOut™ Serum Replacement is widely cited for stem cell culture.
| Classification | Serum-Free |
|---|---|
| Culture Type | Stem Cell (Embryonic, iPS - Induced Pluripotent Stem) |
| Cell Type | Stem Cells (Embryonic),Stem Cells (iPS - Induced Pluripotent Stem) |
| Form | Frozen |
| Serum Level | Serum-Free |
| Product Type | Serum Replacement |
| Quantity | 500 mL |
| Manufacturing Quality | cGMP for medical devices, 21 CFR Part 820 and ISO 13485 |
| For Use With (Application) | Clinical Research, Translational Research |
| Green Features | Sustainable packaging |
| Product Line | KnockOut™ |
| pH | 6 to 8 |
| Shelf Life | 18 Months |
| Shipping Condition | Dry Ice |
| Unit Size | 500 mL |